Project Area A

Projects belonging to Area A are focusing on steady state scenarios. Within these projects we aim at understanding the niche-specific factors that determine Treg cell phenotypes and functions.

Project A01

Dynamics, epigenetic signatures and modulating factors of tissue Treg cell differentiation

Project A02

Role and regulation of muscle-residing Foxp3⁺ Treg cells in health and disease

Project A04

The role of cAMP in regulatory T cell homeostasis and function

Project A05

Regulation of Treg cell subsets and function by the atypical IκB protein Bcl-3

Project A06

Post-transcriptional control of tissue-resident regulatory T cells

Project A07

Investigating Treg cell plasticity in mice and man

Project A08

The role of non-canonical NF-κB signaling in Treg cells in tissue homeostasis and disease

Project A09

CK2 as a molecular switch regulating immunity and tolerance by APC-dependent induction of Treg cells

Project A10

Myeloid cell-regulatory T cell crosstalk in thrombus development and resolution