Project Area B

Area B projects address conditions deviating from the steady state situation. We focus on how diseases affecting the central nervous system, the intestine, or the pancreas alter the Treg cell signatures, allowing us to identify novel strategies for Treg cell-based therapies.

Project B01

Inter- and intramolecular cross-regulation during CNS autoimmunity

Project B02

Impact of CCR4 ligands on tissue Treg cells in islet autoimmunity

Project B03

Induction of Antigen-specific Treg cell responses against airborne antigens

Project B04

Microbiota-induced intestinal Treg cells modulate neuroinflammation

Project B05

In situ reprogramming of dendritic cells for immunomodulation of CNS-specific Foxp3+ regulatory T cells

Project B06

Disease-overarching mechanisms of Treg-CNS interaction

Project B07

Treg cells in the chronically inflamed CNS

Project B08

Treg cells as modulators of gluten-induced inflammation in celiac disease

Project B09

Tissue-derived eicosanoids as modulators of Treg cell induction, stability and function